5/23/2023 0 Comments Delirium novel![]() ![]() Poor sleep and delirium are common problems in older patients. Bundled non-pharmacologic approaches represent a promising framework for prevention and management. Antipsychotics are used widely to prevent and treat delirium, although the efficacy data are equivocal. Delirium is easier to identify, with validated tools available in both ICU and non-ICU settings however, an optimal treatment approach remains unclear. In the hospital setting, poor sleep and delirium are associated with adverse outcomes non-pharmacological interventions are recommended, but tend to be resource intensive and hindered by a lack of reliable sleep measurement tools. Acetylcholine and dopamine are important neurochemicals in the regulation of sleep and wakefulness and their dysregulation has been implicated in development of delirium. Sleep deprivation and delirium are closely linked, with shared clinical characteristics, risk factors, and neurochemical abnormalities. The purpose of this review is to highlight current research on these conditions, their inter-relationship, modes of measurement, and current approaches to management. Poor sleep and delirium are common in older patients but recognition and management are challenging, particularly in the intensive care unit (ICU) setting. ![]()
0 Comments
Leave a Reply. |